Jiaogulan and Cancer

Jiaogulan (gynostemma pentaphyllum) is reported in studies to help the immune system.  A healthy immune system is of immediate help to patients undergoing cancer treatment, particularly those undergoing some form of radiation therapy which tends to depress the immune response. You can read more about this at our antioxidant and immunity links.

Moreover, there is growing research on Jiaogulan's possible direct inhibitory effects on tumor cells.


The science behind Jiaogulan

More research is needed. Jiaogulan is an herbal supplement and not a medicine, treatment or cure. However it may be a helpful supplement to cancer therapy.

Potential Direct Inhibitory Effects on Tumors

Wang, C. et al. A preliminary observation of preventive and blocking effect of Gynostemma pentaphyllum (Thunb) Makino on esophageal cancer in rats. Hua Xi Yi Ke Da Xue Xue Bao. 1995

 In this study researchers found that rats injected with a known carcinogen developed fewer and less frequent tumors when allowed to ingest water infused with Jiaogulan. The development of cancer was also delayed by about 6 weeks suggesting to the researchers that Jiaogulan was having a direct inhibitory effect.

Study concludes Jiaogulan kills liver cancer cells

Chen JC et al. Gypenoside induces apoptosis in human Hep3B and HA22T tumour cells. Cytobios. 1999.

Dr. Chen and his team, found that human liver cancer cells treated for two days with gypenosides (the active ingredients in Jiaogulan) died via apoptosis. Normal cells in the cancerous tissue sample proliferated.

Qwa-fu Wang, et al. Regulation of Bcl-2 family molecules and activation of caspase cascade involved in gypenosides-induced apoptosis in human hepatoma cells. Cancer Letters 2002

Reseachers at the Chinese Medical College  in Taiwan  studied the mechanism by which Jiaogulan kills liver cancer cells. They confirmed the results of the above study and identified a potential mechanism for this effect.

Scientists  say Jiaogulan has "a positive anti-carcinogen effect"!

Zhou Z. et al. Effect of gynostemma pentaphyllum mak on carcinomatous conversions of golden hamster cheek pouches induced by dimethylbenzanthracene: a histological study.The Journal of Chinese Medicine 1998.

Dr. Zhou at Shanghai Medical University gave hamsters a known carcinogen. A control group did not receive Jiaogulan and developed cancer as predicted. Two other groups were given Jiaogulan orally. Both groups showed remarked slowing of the cancerous growth. The inhibitory effects were directly correlated with the dosage amounts of Jiaogulan.




Improved Immune Systems in the Presence of Radiation!

Chen WC et al. Protective effects of Gynostemma pentaphyllum in gamma-irradiated mice. American Journal of Chinese Medicine 1996.

In this study researchers were interested in the effects on the immune system of radiation. They subjected mice to gamma radiation. They found reduced white blood cell counts  as a result of the radiation treatment. However, Mice given Jiaogulan recovered their white blood cell counts more quickly.

Jiaogulan found to inhibit cervix cancer!

Chiu TH et al.N-acetyltransferase is involved in gypenosides-induced N-acetylation of 2-aminofluorene and DNA adduct formation in human cervix epidermoid carcinoma cells (Ca Ski). In Vivo May 2003.

Dr. Chiu and his team studied the inhibitory effects of gypenosides on human cervix cancer. They found there is indeed an inhibitory effect. The mechanism appears to be that gypenosides inhibited NAT mRNA expression in human cervix cancer cells.

Our Jiaogulan tea is grown under strict organic quality control standards in the highlands of Thailand. We dry the tea in loose leaf form at the farm and we ship fresh to the US each month to maintain maximum potency. Unlike many herbals, Jiaogulan tastes great hot or cold. We were awarded the prize for best tasting tea in Thailand by the Thai Agriculture Ministry.
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Useful Cancer Related Sites:

The Wellness Directory of Minnesota has an excellent run down on alternative cancer therapies.

The Cancer Cure Foundation describes themselves as "The ultimate one-stop source for information about alternative cancer treatments, therapies and clinics."

  Disclaimer: This discussion is for informational purposes only. The Immortalitea Company™ is not responsible for the accuracy of the medical benefits discussed. The medical conditions discussed above are serious medical conditions. You should consult your physician regarding the proper treatment of these conditions. Discuss with your physician any reactions to or potential drug interactions with our products. These claims have not been evaluated by the USA Food and Drug Administration. This product is not intended to diagnose, treat or cure any disease.